Impact of methicillin-resistant Staphylococcus aureus bloodstream infec-tion on the prognosis of patients
10.3969/j.issn.1671-9638.2015.01.006
- VernacularTitle:血流感染耐甲氧西林金黄色葡萄球菌对患者预后的影响
- Author:
Long ZHOU
;
Fu QIAO
;
Wenzhi HUANG
;
Zhiyong ZONG
- Publication Type:Journal Article
- Keywords:
Staphylococcus aureus;
methicillin-resistant Staphylococcus aureus;
methicillin-susceptible Staphy-lococcus aureus;
length of hospital stay;
prognosis;
healthcare-associated infection
- From:
Chinese Journal of Infection Control
2015;(1):27-30
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the impact of methicillin-resistant Staphylococcus aureus (MRSA)blood-stream infection on the length of hospital stay,hospital mortality,and poor prognosis of patients.Methods 357 patients with Staphylococcus aureus (S .aureus)bacteremia in a hospital between January 1 ,2009 and December 31 , 2013 were surveyed and analyzed retrospectively.Results Of 357 patients,91 were infected with MRSA and 266 with methicillin-susceptible S .aureus (MSSA).The length of hospital stay was statistically different between MR-SA and MSSA group(29 d vs 23 d,P <0.01);before infection,length of hospital stay of MRSA group was longer than MSSA group(P <0.01 );after infection,length of hospital stay was not statistically different between two groups(17 d vs 16.5 d,P = 0.92 ).Mortality of MRSA group and MSSA group was not statistically different (13.19% vs 9.02%,χ2 =1 .28,P =0.26).The incidence of poor prognosis of MRSA group was higher than MSSA group(29.67% vs 16.92%,χ2 =6.85,P =0.01 ).Multivariate analysis results showed that MRSA infection was independent risk factor for poor prognosis (P <0.01).Conclusion MRSA infection doesn’t contribute to the pro-longation of hospital stay,but MRSA bloodstream infection is a risk factor for poor prognosis of patients.
