Application of single-dose dexmedetomidine infusion in patients undergoing percutaneous dilatational tra-cheostomy
10.3969/j.issn.1001-3733.2015.01.020
- VernacularTitle:单次输注右美托咪定在经皮扩张气管切开术中的临床应用
- Author:
Rongxiang SU
;
Yun SHAO
;
Gang LI
;
Xiaoping GU
- Publication Type:Journal Article
- Keywords:
Dexmedetomidine;
Single-dose infusion;
Monitored anesthesia care;
Percutaneous dilatational tra-cheostomy(PDT);
Hemodynamics
- From:
Journal of Practical Stomatology
2015;(1):88-91
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical effects of dexmedetomidine(DDM)under monitored anesthesia care(MAC)in oral and maxillofacial patients undergoing percutaneous dilatational tracheostomy(PDT).Methods:38 patients with oral and maxillofa-cial tumor undergoing PDT before surgery were randomly assigned into 2 groups(n =19).Patients in group D received a single-dose DDMof 0.5 μg/kg infused for 10 min;those in group Mreceived 2 mg of midazolam and 1 μg/kg of fentanil.Then all patients were given local anesthesia followed by PDT.MAP,HR and SpO2 were monitored before (T0 )and after drug administration (T1 ),at T2 (skin incision)and T3 (insert dilation catheter).Ramsay scorce,bucking,respiration depression and adverse cardiovascular reaction were recorded.All patients were followed up 24 h postoperatively for the observation of adverse recall of PDT.Results:Compared with T0 ,at T1 ,T2 MAP and HR in group D were lower,but MAP and HR at T3 in group Mwere higher(P <0.05).At T1 ,T2 and T3 ,MAP and HR in group D were significantly lower than those in group M(P <0.05).During operation,the incidence of bucking and respiration depression in group D was lower than that in group M(P <0.05).Conclusion:During PDT operation under MAC,a single-dose dexmedetomidine is effective in stablizing hemodynamics,reducing bucking and respiration depression.
