Effects of modified radical mastectomy combined with chemotherapy on complications and quality of life in patients with breast cancer
10.3969/j.issn.1005-6483.2015.02.018
- VernacularTitle:乳腺癌改良根治术联合化疗对患者并发症与生活质量的影响
- Author:
Quanyuan LI
;
Liqin YAN
;
Jian WEI
- Publication Type:Journal Article
- Keywords:
quality of life;
breast cancer;
complications;
modified radical mastectomy
- From:
Journal of Clinical Surgery
2015;(2):132-134
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of modified radical surgery combined with chemo-therapy on postoperative complications and quality of life in breast cancer patients.Methods The clinical data of 175 patients with early breast cancer were retrospective analyzed.According to the different ways of surgical treatment,patients were divided into the control group(n =100)and the study group(n =75).In the study group,patients received modified radical mastectomy,and preoperative and postoperative chemo-therapy as adjuvant therapy.In the control group,patients received traditional standard radical surgery.The follow-up ranged from 1 to 3 years.Recurrence,mortality,postoperative complications,and quality of life were compared between the two groups.Results There were no significant differences in local recurrence (6.7% vs 6%)and axillary lymph node recurrence (2.7% vs 3%),distant metastasis (10.7% vs 11%),and 5-year survival rate(92% vs 91%)between the study group and control group(P >0.05).In the study group,the incidence of postoperative complications was significantly lower(6.7% vs 42%), while its score on quality of life significantly improved(P <0.05).Conclusion For early breast cancer, modified radical mastectomy combined with chemotherapy has similar effects as the standard radical mas-tectomy.It has obvious advantages in reducing complications and improving the quality of life,which is worthy of being spread clinically.
