A Case of Ectopic ACTH Syndrome Caused by Thymic Carcinoid Tumor and Localized by PET.
- Author:
Jong Chul WON
1
;
Sung Kwan HONG
;
Hyun Ju LEE
;
Sang Ook KIM
;
Yun Hee JEONG
;
Dae Hyuk MOON
;
Dong Kwan KIM
;
Kyung Yub KONG
;
Jae Sung LEE
;
Ki Soo KIM
Author Information
1. Division of endocrinology, Department of Internal medicine, Ulsan university, College of medicine, Asan Medical Center, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Ectopic ACTH syndrome;
PET;
Thymic carcinoid
- MeSH:
ACTH Syndrome, Ectopic*;
Adrenocorticotropic Hormone;
Carcinoid Tumor*;
Diagnosis;
Drug Therapy;
Early Diagnosis;
Humans;
Ketoconazole;
Lung Neoplasms;
Radiotherapy;
Sepsis
- From:Journal of Korean Society of Endocrinology
1999;14(4):771-778
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Ectopic ACTH syndrome is frequently caused by lung cancer and uncommonly by other tumors such as thymic carcinoid. For its treatment, early diagnosis and complete resection is irresponsible, but some cases are remained unlocalized in spite of all diagnostic modalities. Here we report a case of ectopic ACTH syndrome which was localized by PET but could not be localized by conventional technique. A tumor at thymic area was ACTH secreting thymic carcinoid which was operated but couldnt resect completly. Glucocorticoid hypersecretion was persisted with chemotherapy, radiotherapy, and ketoconazole treatment. Patient died of sepsis after 12 months of diagnosis.
