Significance of serum IL-17,IL-23 in patients with allergic rhinitis
10.3969/j.issn.1000-484X.2015.02.026
- VernacularTitle:变应性鼻炎患者血清IL-17和IL-23的表达及临床意义
- Author:
Liangbo LI
;
Junwu TAN
;
Hong PENG
;
Cheng GONG
;
Xueqiu CAO
;
Yong LIAO
- Publication Type:Journal Article
- Keywords:
Allergic rhinitis;
Interleukin-17;
Interleukin-23
- From:
Chinese Journal of Immunology
2015;(2):247-249
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the expression level of IL-17,IL-23 in patients with allergic rhinitis (AR) and their clinical significance.Methods:A total of 25 patients with AR were treated as observe group , and 23 healthy volunteers were chosen as the control group.The levels of serum IL-17,IL-23 and specific-IgE ( s-IgE) were compared between the two groups.The relationships among serum IL-17,IL-23 and sIgE in patients with AR were discussed.Results:The levels of IL-17,IL-23 and sIgE in observe group were significantly higher than in control group.There was a positive linear correlation between the IL-17 and IL-23/the IL-23 and sIgE/the sIgE and IL-17 in observe group.Conclusion: The IL-17 , IL-23 might be the two important cytokine in the occurrence and development process of allergic rhinitis.The IL-17,IL-23 might be related to the formation of sIgE.
