Advances in pathogenesis of children with chronic refractory immune thrombocytopenia
10.3760/cma.j.issn.2095-428X.2015.03.002
- VernacularTitle:儿童慢性难治性血小板减少症发病机制研究
- Author:
Min XIA
- Publication Type:Journal Article
- Keywords:
Chronic refractory autoimmune thrombocytopenia;
Pathogenesis;
Acquired;
Genetic
- From:
Chinese Journal of Applied Clinical Pediatrics
2015;30(3):164-167
- CountryChina
- Language:Chinese
-
Abstract:
Chronic refractory autoimmune thrombocytopenia (C/RITP) comprises complex and heterogeneous pathogenesis.Beyond the classic immune disorders such as platelet autoantibodies and cellular immune imbalance,other important considerations that can cause acquired C/RITP include infection,drug,vaccines,autoimmune diseases,tumor,or platelet function disorder.In addition,advances in the molecular mechanism and genetic correlations of C/RITP for children are also discussed.
