Open fracture repair：wound infection, implant selection and evaluation of prognosis
10.3969/j.issn.2095-4344.2015.26.030
- VernacularTitle:开放性骨折修复：创面感染、植入物选择及预后评价
- Author:
Xiangyu MA
;
Dong WANG
- Publication Type:Journal Article
- Keywords:
Fractures,Open;
Prostheses and Implants;
Debridement
- From:
Chinese Journal of Tissue Engineering Research
2015;(26):4258-4264
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:Open fractures often present soft-tissue defects, high-risk infection, and fracture with bone defect, often lead to more postoperative complication, defect of limb function, and bring great difficulties to clinical treatment. There is some controversy in the treatment of such fracture. Relevant animal experiment and clinical study become the hotspot in recent years. OBJECTIVE:To review some controversy about open fracture treatment and latest research. METHODS:A computer-based online search of China National Knowledge Infrastructure database and PubMed was performed for articles published from January 2005 to January 2015. Key words included “Open fracture, Evaluation and prognosis of injury, Antibiotics, Debirdement, Treatment of fracture, Wound repair”. More than 100 literatures were retrieved, and 47 articles met the inclusion criteria. RESULTS AND CONCLUSION:After a large number of animal experiments and clinical application, open fracture debridement, prevention of infection, implant selection and evaluation of prognosis had been deeply studied, especialy the study of implant treatment of bone defects. Metal three-dimensional printer has changed the traditional concept of implant. Nano titanium dioxide /PEEK bioactive composite materials have become a hot research in recent years.
