Research progress on the relationship between FAK and cancer
10.3969/j.issn.1000-8179.20141430
- VernacularTitle:FAK与肿瘤关系的研究进展
- Author:
Lingmei LI
;
Wenfeng CAO
- Publication Type:Journal Article
- Keywords:
focal adhesion kinase;
cancer;
metastasis;
apoptosis
- From:
Chinese Journal of Clinical Oncology
2015;(2):116-119
- CountryChina
- Language:Chinese
-
Abstract:
Focal adhesion kinase (FAK), a type of protein tyrosine kinase in the cytoplasm, is highly expressed in many types of malignant tumors. FAK is named as such because of its close relationship with the cell adhesion function. Recent studies show that FAK is expressed in many tumor cells and has a definite relationship with cancer progress, metastasis, and prognosis. Accordingly, FAK has become one of the new tumor therapeutic targets that will bring new methods for tumor therapy.