Surveillance of antibiotic resistance in gram-negative bacilli strains collected from Chuzhou First Hospital during 2013
- VernacularTitle:安徽省滁州市第一人民医院2013年临床分离的革兰阴性杆菌耐药性分析
- Author:
Qiang XIE
;
Mingjie CAO
;
Jinli WANG
;
Tiantian XU
- Publication Type:Journal Article
- Keywords:
gram-negative bacillus;
antibiotic;
drug resistance
- From:
Chinese Journal of Infection and Chemotherapy
2015;(1):67-69
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution and antibiotic resistance of gram-negative bacilli for better antimicrobial therapy in our hospital.Methods A retrospective analysis was conducted for the 1 060 strains of gram-negative bacilli isolated from clinical specimens during 2013.Results Of the 1 060 gram-negative bacterial strains isolated during 2013,E.coli,K . pneumoniae,P .aeruginosa and A.baumannii were the leading pathogens,accounting for 29.3%,22.8%,11.5% and 9.9%,respectively.The prevalence of extended spectrum-lactamases (ESBLs)positive strains was 63.7%,32.2% and 28.0% in E.coli,K .pneumoniae and P .mirabilis,respectively.The Enterobacteriaceae strains were highly sensitive to carbapenems.The percentage of the P .aeruginosa isolates resistant to meropenem,imipenem or amikacin was lower than 30%.The percentage of the Acinetobacter spp.(A.baumannii accounted for 70.9%)strains resistant to meropenem and imipenem were 25.0% and 26.2%.Conclusions Most of the gram-negative bacilli are resistant to multiple antimicrobial agents. We should strengthen the monitoring of the antibiotic resistance of gram-negative bacilli and optimize antimicrobial therapy.
