Influence of repeated TACE treatment interval on the prognosis of hepatocellular carcinoma

VernacularTitle:重复 TACE 治疗周期对原发性肝癌预后的影响
Author: Yijun ZHANG ; Yefa YANG ; Shuqun SHEN ; Naijian GE ; Jun LIANG ; Lu WU ; Xiaohe YU ; Zhiyong SHI ; Dong WU ; Mengchao WU
Publication Type:Journal Article
Keywords: hepatocellular carcinoma; transarterial chemoembolization; repetition period; prognosis
From: Journal of Practical Radiology 2015;(5):824-828
CountryChina
Language:Chinese
Abstract: Objective To investigate the effects of transarterial chemoembolization (TACE)treatment interval on the prognosis of patients with advanced hepatocellular caisinoma(HCC).Methods We retrospectively collected clinical data of 123 advanced HCC patients treated with repeated TACE.The patients were divided into two groups (group A with fixed repeated treatment interval and group B with that according to the clinical needs).Cox regression,survival curve and log-rank test were used to assess the effects of the treat-ment intervals on prognosis.Results The treatment intervals of the group A and group B were (1.1±0.3)months and (3.0±1.5) months,respectively (P <0.001).Multivariate Cox analysis showed the efficacy (P =0.024)and repetition periods (P <0.001 ) were independent prognostic factors.Conclusion TACE interval is independent risk factor for the prognosis of patients with ad-vanced HCC.Repeated TACE treatment according to clinical needs may be more favorable for prognosis of the patients.