The advances of genetic factors in spontaneous intracerebral hemorrhage and molecular mechanisms
10.11958/j.issn.0253-9896.2015.07.032
- VernacularTitle:自发性脑出血的遗传因素及其分子机制的研究进展
- Author:
Yang LIU
;
Xiu LIU
;
Xuyi CHEN
;
Shengkai SUN
;
Zhihong WANG
- Publication Type:Journal Article
- Keywords:
cerebral hemorrhage;
genetic polymorphism;
pathogenesis;
smolecular mechanisms;
genetic factors;
review
- From:
Tianjin Medical Journal
2015;(7):818-821
- CountryChina
- Language:Chinese
-
Abstract:
Spontaneous intracerebral hemorrhage (SICH) refers the primary, non-traumatic parenchymal hemorrhage. In China, SICH accounts for about 20%-30%of total strokes. SICH is a kind of disease affected by multiple factors includ?ing environmental and genetic factors. The high morbidity and mortality cause serious damage to human health. Therefore, it is important to find etiology and risk factors of SICH. The article reviewed the progress of SICH pathogenesis in the perspec?tive of genetics and molecular biology.