Advanced study on microRNAs involved in prevention and treatment of respiratory system diseases
10.3969/j.issn.1001-1978.2015.07.002
- VernacularTitle:MicroRNAs在呼吸系统疾病预防和治疗中的研究进展
- Author:
Xiaoli LIU
;
Rufeng WANG
;
Xiuhua HU
- Publication Type:Journal Article
- Keywords:
microRNA;
virus infectious respiratory disease;
pulmonary fibrosis;
asthma;
COPD;
pulmonary tuberculosis;
lung cancer
- From:
Chinese Pharmacological Bulletin
2015;(7):895-899
- CountryChina
- Language:Chinese
-
Abstract:
Recently, along with the harmful factors in air in-creasing, the incidence of respiratory system diseases has been gradually rising. Therefore, more studies are focused on impro-ving the prevention and treatment on respiratory system diseases. Current researches have shown that microRNAs ( miRNA ) con-tribute to the prevention and treatment on respiratory system dis-eases, including virus infectious respiratory disease, pulmonary fibrosis, asthma, COPD, pulmonary tuberculosis and lung canc-er. The up-regulation and down-regulation of microRNAs could effectively regulate the biological process of these diseases. The review analyzes the recent years′study results of respiratory sys-tem diseases and microRNAs in depth, and discuss the role of microRNA in the treatment and prevention of respiratory disea-ses. Moreover, in this review we can provide new knowledge a-bout respiratory diseases and development of more potent drug targets for the treatment and prevention of respiratory diseases.
