On function of long noncoding RNA
10.3969/j.issn.1001-1978.2015.07.003
- VernacularTitle:长非编码RNA的功能研究
- Author:
Huaide JIANG
;
Guilin LI
- Publication Type:Journal Article
- Keywords:
long noncoding RNA;
aging;
diseases related to ag-ing;
transcriptome analysis;
the research methods;
bioinformat-ics
- From:
Chinese Pharmacological Bulletin
2015;(7):900-905
- CountryChina
- Language:Chinese
-
Abstract:
Long noncoding RNAs ( lncRNAs ) are transcribed RNA molecules greater than 200 nucleotides in length. In recent years, studies have shown that lncRNAs have many important bi-ological functions. With the development of modern biological technology, lncRNAs transcripts can be easily detected and pre-dicted. However, unlike protein-coding genes whose sequence motifs usually have indicative function, lncRNA sequence infor-mation is currently uninformative for function prediction. Thus, how to decode the function of lncRNAs has gradually become a hot issue in genome research. The paper summarizes the studies regarding the methods to probe the function of lncRNAs.
