Advances in non-viral vector research of siRNA
10.3969/j.issn.1001-1978.2015.07.005
- VernacularTitle:非病毒siRNA载体研究进展
- Author:
Zhonghua CHEN
;
Desheng ZHU
;
Jun LI
;
Zhanqin HUANG
- Publication Type:Journal Article
- Keywords:
siRNA,delivery;
vector;
liposome;
polymer;
cell-penetrating peptides;
aptamer
- From:
Chinese Pharmacological Bulletin
2015;(7):910-914
- CountryChina
- Language:Chinese
-
Abstract:
siRNA drug research and development is becoming one of the main objectives in the future. However, due to the in-stability of siRNA and the complex environment in vivo, the safe and effective delivery of siRNA is limited in vivo. Thus, special vectors are used to assist siRNA to express biological effects. This paper reviews the advances in non-viral vector for delivery of siRNA in vivo.
