Effect of Shuxuening combined with creatine phosphate sodium in detecting ischemia modified albumin on acute severe carbon monoxide poisoning
10.3969/j.issn.1006-5725.2014.24.022
- VernacularTitle:急性一氧化碳中毒应用舒血宁及磷酸肌酸钠前后检测缺血修饰白蛋白的意义
- Author:
Jing LI
;
Guoying MANG
;
Ye PENG
;
Juan LIU
;
Yan WANG
;
Weizhen WANG
;
Lan WANG
- Publication Type:Journal Article
- Keywords:
Acute carbon monoxide poisoning;
Ischemia modified albumin;
Treatment
- From:
The Journal of Practical Medicine
2014;(24):3943-3945
- CountryChina
- Language:Chinese
-
Abstract:
Objective Study of Shuxuening combined with sodium phosphocreatine on acute severe carbon monoxide poisoning with ischemia modified albumin level and its curative effect in patients. Methods 66 cases of ASCOP patients were randomly divided into routine group and treatment group, all patients were detected for myocardial enzymes, cTnI, IMA before treatment, after treatment 6 h and 3 d. Results IMA was significantly decreased before treatment, while no significant changes occurred in myocardial enzymes and cTnIn levels. After treatment for 6 h, IMA in treatment group was higher than conventional group (P < 0.05). Myocardial enzymes and cTnI gradually increased, the two groups had no difference (P>0.05). After treatment for 3d, cTnI level of normal group increased obviously compare with the treatment group (P>0.05). Myocardial enzymes, IMA restored to the normal level (P>0.05). The level of cTnI after treatment for 3 d improved compare with 6 h. Conclusion Treatment of early ASCOP patients by Shuxuening combined with sodium phosphocreatine significantly improve the recovery of myocardial injury poisoning. The level of IMA can be used as evaluation index of myocardial ischemia and drug treatment.
