Association of CRP and D-Dimer with secondary pulmonary hypertension in patients with AECOPD
10.3969/j.issn.1006-5725.2014.24.024
- VernacularTitle:CRP及D-Dimer在慢性阻塞性肺疾病急性加重期继发肺动脉高压中的相关性
- Author:
Cong JIN
;
Xiangzeng HUANG
- Publication Type:Journal Article
- Keywords:
Chronic obstructive pulmonary disease;
Pulmonary hypertension;
C-reaction protein;
D-Dimer
- From:
The Journal of Practical Medicine
2014;(24):3949-3951
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical significance of C-reaction protein ( CRP ) and D-Dimer levels in patients with acute exacerbation of chronic obstructive pulmonary disease ( AECOPD ) complicated by pulmonary hypertension (PH) and their association with HP. Methods Arterial blood gas and levels of CRP and D-Dimer were detected in 150 patients with AECOPD. Results Levels of CRP, D-Dimer, and PaCO2 were higher but PO2 level was lower in patients with moderate to severe PH than those with mild PH and the control subjects. Levels of CRP and D-Dimer were higher in patients with mild PH than the control subjects. Levels of CRP, D-Dimer, and PCO2 levels had a linear relationship with PASP, while PO2 was negatively correlated with PASP. Levels of CRP and D-Dimer were positively related with PCO2, while were negatively correlated with PO2. Conclusions Levels of CRP and D-Dimer can be used as an indicator for estimating the severity of pulmonary hypertension in patients with AECOPD.
