Correlation study of Narcotrend values and patient-controlled sedation of dexmedetomidine under CSEA
10.3969/j.issn.1006-5725.2014.23.003
- VernacularTitle:腰硬联合麻醉下右美托咪定自控镇静与Narcotrend值的相关性分析
- Author:
Xingan ZHANG
;
Chuanmu QIAN
;
Weidong SHAO
;
Bo XU
;
Weifeng TU
- Publication Type:Journal Article
- Keywords:
Narcotrend;
Dexmedetomidine;
Patient-controlled sedation;
CSEA
- From:
The Journal of Practical Medicine
2014;(23):3716-3719
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation of patient-controlled sedation of dexmedetomidine and Narcotrend values. Methods Forty patients with lower limb surgery were enrolled. Until CSEA block fixed , the electronic pump ran the patient-controlled sedation of dexmedetomidine. The parameter of electronic pump was set as follows: load dose 2 mL + background dose 1.5 mL/h + single dose 0.5 mL + locktime 20 s. The heart rate , mean arterial pressure, pressing times, effective times, OAA/S sedation scores and NI values were determined. Results At T4 point, the patients reached appropriate sedation. At T4 ~ T9 OAA/S scores kept 3 to 4. From T5 point, NI values showed significant decrease. After the T7 point. OAA/S scores and NI values reached the plateau time of (7.5 ± 1.8) min and (13.1 ± 3.4) min, OAA/S scores of 1, 2, 3, 4, respectively, corresponding roughly with NI values 95 to 100, 90 to 94, 65 to 89, 40 to 64. The correlation coefficient was 0.58. The time of NI values significant decreased in the younger group and in the elderly group, with (10.2 ± 1.6) min and (14.4 ± 2.2) min. In T5~ T9 point, NI values of the younger group were significantly lower than those in the elderly group. Conclusion Relevant relationships are observed between dexmedetomidine patient-controlled sedation depth and the narcotrend values under CSEA.
