Sedative effect of different speed of intravenous infusion of dexmedetomidine detected by Narocotrend index on elderly patients
10.3969/j.issn.1006-5725.2014.23.004
- VernacularTitle:Narcotrend 指数监测下不同速度泵注右美托咪啶对老年患者镇静效应的影响
- Author:
Jinhe DENG
;
Yongyong SHI
;
Weixian ZHAO
;
Xiaoxing CHEN
;
Yuze LI
- Publication Type:Journal Article
- Keywords:
Dexmedetomidine;
Spinal anesthesia;
Elderly patients;
Narcotrend monitoring
- From:
The Journal of Practical Medicine
2014;(23):3720-3722
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the sedative effects and the adverse reactions in the elderly patients received different speed of dexmedetomidine (Dex) intravenous infusion. Methods Eighty elderly cases were randomly divided into four groups. Group D0 was the control group, while the group D1, D2 and D3 were the trial groups. The heart rates, blood pressure, SpO2, Ramsay sedation score and Narcotrend value were recorded. Results The sedation onset time of the D2, D3 group was faster than those in the D0 and D1 groups (P <0.05, respectively), and the duration of sedation in groups D2 and D3 were significantly longer than that in the D0 and D1 groups (P < 0.05). Among the four groups, no significant differences in the incidence of hypotension or bradycardia needed vasopressors or atropine to treat and oxygen saturation were shown (P > 0.05). Conclusion Intravenous infusion of Dex by doses of 0.75 ~ 1.0 μg/(kg·h) during hip surgery in the elderly patients under spinal anesthesia could lead to a safe and effective sedation.
