Nasal resistance in patients with obstructive sleep apnea hypopnea syndrome and the effect of nCPAP
10.3969/j.issn.1006-5725.2014.24.006
- VernacularTitle:阻塞性睡眠呼吸暂停低通气综合征患者的鼻阻力及nCPAP治疗后的影响
- Author:
Yingying REN
;
Xiaofen SU
;
Nuofu ZHANG
- Publication Type:Journal Article
- Keywords:
Obstructive sleep apnea hypopnea syndrome;
nCPAP;
Nasal resistance
- From:
The Journal of Practical Medicine
2014;(24):3896-3899
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe nasal resistance in healthy adult people and patients with obstructive sleep apnea hypopnea syndrome (OSAHS), comparing the changes in nasal resistance after nCPAP treatment, and to explore the role of nasal resistance in development of OSAHS and the effect of nCPAP on nasal resistance. Methods Detection of nasal resistance was performed in 11 healthy people and 40 patients with OSAHS after completion of polysomnography (PSG). Three weeks after treatment with nCPAP, the patients received polysomnography and detection of nasal resistance again. Results Nasal resistance was higher in patients with OSAHS than healthy people [(0.27 ± 0.9)Pa/(cm3·s) vs. (0.21 ± 0.7)Pa/(cm3·s), t=-2.048, and P<0.05];nasal resistance was not related with age, BMI, neck circumference, waistline, AHI, MinSO2, and ODI (P>0.05). MinSO2, AHI and ODI were markedly improved three weeks after nCPAP therapy (P<0.05). Nasal resistance was increased from (0.27 ± 0.1) Pa/(cm3·s) to (0.43 ± 0.3)Pa/(cm3·s) after treatment (t = -2.733, P < 0.05). Conclusions Increased nasal resistance is one of risk factors for pathogenesis of OSAHS. Nasal resistance is not related with the severity of OSAHS. nCPAP can lead to an elevation in nasal resistance.
