Rapid Assessment of Critical Quality Attributes of Chinese Materia Medica：Visualization Technology of Near Infrared Chemical Imaging
10.11842/wst.2014.12.009
- VernacularTitle:中药关键质量属性快速评价：近红外化学成像可视化技术＊
- Author:
Luwei ZHOU
;
Zhisheng WU
;
Xinyuan SHI
;
Yanling PEI
;
Yanjiang QIAO
- Publication Type:Journal Article
- Keywords:
Near-infrared chemical imaging;
process analysis technology;
critical quality attributes of Chinese materia medica;
visualization;
image analysis
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2014;(12):2568-2574
- CountryChina
- Language:Chinese
-
Abstract:
Near infrared chemical imaging (NIR-CI) is an emerging technology for rapidly analyzing the critical quality attribute of Chinese materia medica (CMM). It integrates NIR spectroscopy with chemical imaging. In this paper, it provided a systematic introduction to NIR-CI, such as the core part of instrument, the reliability, transformation, analysis and application of high-dimensional data acquisition. In addition, current studies of NIR-CI application in pharmaceutical field were analyzed. Finally, future opportunities and challenges of NIR -CI applications in the quality control of CMM preparation were prospected.
