Study on Drug Compatibility between Ginkgolides Meglumine Injection and Neutral Borosilicate Glass Ampoule
10.11842/wst.2014.12.027
- VernacularTitle:银杏二萜内酯葡胺注射液与中性硼硅玻璃安瓿的药物相容性试验研究*
- Author:
Xuefeng LI
;
Feng LI
;
Lili LIU
;
Yingchun WEI
;
Yun WU
;
Wei XIAO
- Publication Type:Journal Article
- Keywords:
Compatibility;
ginkgolides;
packaging materials;
neutral borosilicate glass ampoule
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2014;(12):2676-2680
- CountryChina
- Language:Chinese
-
Abstract:
This article was aimed to determine the feasibility of neutral borosilicate glass ampoule as the inner packing material of Ginkgolides meglumine injection by studying the drug compatibility between Ginkgolides me-glumine injection and neutral borosilicate glass ampoule. On the basis of the Pharmaceutical Packaging Materials and Drug Compatibility Test Guidance Rules, the study was carried on the compatibility between Ginkgolides me-glumine injection and neutral borosilicate glass ampoule for packaging materials. The results showed that no mi-gration or adsorption quality of change between the Ginkgolides meglumine injection and neutral borosilicate glass ampoule. It had good compatibility between neutral borosilicate glass ampoule and Ginkgolides meglumine injec-tion. It was concluded that neutral borosilicate glass can be used as the packing materials of Ginkgolides meglumine injection.