Experimental observation of aesthetic effects of introducing diazepam into combined aesthesia of Sumianxin and Ketamine hydrochloride
10.3969/j.issn.1671.7856.2015.001.013
- VernacularTitle:引入地西泮对速眠新复合氯胺酮麻醉效果的改进观察
- Author:
Chunyan CAO
;
Ning KANG
;
Li YAN
;
Zhengyun HU
;
Zhihui SHEN
;
Ran XIAO
- Publication Type:Journal Article
- Keywords:
Anesthesia;
Sumianxin;
Ketamine hydrochloride;
Diazepam;
Rabbit
- From:
Chinese Journal of Comparative Medicine
2015;(1):71-75
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effectiveness of introducing Diazepam into combined aesthesia of Sumianxin and ketamine hydrochloride .Method A total of 80 rabbits of both genders for operation were randomly divided into A , B and C groups .The A group was injected with Sumianxin intramuscularly ( 0.3 mL/kg by weight ) .The B group was injected with Sumianxin and ketamine hydrochloride intramuscularly ( 0.3 mL/kg by weight ) .The C group was injected with Diazepam intravenously ( 1.5 mL/kg by weight ) combined with Sumianxin and ketamine hydrochloride injected intramuscularly (0.3 mL/kg by weight).The aesthetic effects, induction time, anesthesia maintaining time, total anaesthetic dose and operation time were observed , recorded and compared .Result The induction time of the C group was significantly shorter than A and B groups (P<0.01).The initial anesthesia maintaining time of the C group was the longest among the three (P<0.01) with least total anaesthetic dose (P<0.01).The operation time of the C group was the least with best aesthetic effects (P<0.01).Conclusion Introducing Diazepam into combined aesthesia of Sumianxin and ketamine hydrochloride can improve the aesthetic effects .Therefore , this is an optional aesthetic method for time-consuming animal operation or sensitive surgical sites of rabbits .
