18F-FDG PET/CT in Diagnosis of Small Intestinal Malignant Neoplasm
10.3969/j.issn.1005-5185.2015.01.006
- VernacularTitle:18F-FDG PET/CT诊断小肠恶性肿瘤的价值
- Author:
Chongyang DING
;
Tiannv LI
- Publication Type:Journal Article
- Keywords:
Intestinal neoplasms;
Positron-emission tomography;
Tomography,spiral computed;
Fluorodeoxyglucose F18;
Lymphoma,non-Hodgkin;
Adenocarcinoma;
Diagnosis,differential;
Pathology,surgical
- From:
Chinese Journal of Medical Imaging
2015;(1):19-22
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To analyze the 18F-FDG PET/CT features of small intestinal malignant neoplasm, and to discuss the diagnosis value. Materials and Methods Forty-seven patients who were highly suspected with small intestinal tumors underwent 18F-FDG PET/CT whole body scan were retrospectively analyzed, the results of PET/CT examinations and the findings of biopsy and surgical pathology were compared. The maximum of intestinal wall thickness (IWTmax) and maximum of standardized uptake value (SUVmax) were calculated to analyze the relationship of them under different pathological conditions. Results Six out of the 47 small intestinal tumors were benign, the other 41 were malignant tumors among which 19 were malignant lymphoma and 17 were adenocarcinoma. The sensitivity, specificity, accuracy rate, positive predictive value and negative predictive value of 18F-FDG PET/CT in the diagnosis of small intestinal malignant neoplasm were 92.7%, 83.3%, 91.5%, 97.4% and 62.5%, respectively. Compared with those of benign tumors, the SUVmax and IWTmax of malignant intestinal tumors were significantly higher (t=5.596 and 2.376, P<0.05). The SUVmax in small bowel adenocarcinoma was significantly lower than that in malignant lymphoma (t=2.419, P<0.05);the IWTmax. between the two kinds of tumors showed no difference (t=0.369, P>0.05). The SUVmax and IWTmax of small intestinal malignant lymphoma had no correlation (r=0.293, P>0.05), whilst there was significant correlation between the IWTmax and SUVmax in small intestinal adenocarcinoma (r=0.542, P<0.05). Conclusion The SUVmax and IWTmax of malignant intestinal tumors are higher than those of benign intestinal tumors; 18F-FDG PET/CT imaging is rather reliable in differentiating small intestinal malignant tumors from benign ones. Intestinal malignant lymphoma shows a higher uptake of 18F-FDG than intestinal adencarcinoma, but the intestinal wall thickness of the two kinds shows no difference.
