Two Cases of Malignant Schwannoma in Association with Neurofibromatosis.
10.5021/ad.1991.3.2.119
- Author:
Seon Jong KIM
;
Jung Uk YI
;
Young Suck RO
;
Chan Kum PARK
;
Jae Hong KIM
- Publication Type:Case Report
- Keywords:
Malignant schwannoma;
Neurofibromatosis
- MeSH:
Arm;
Female;
Humans;
Lost to Follow-Up;
Neurilemmoma*;
Neurofibromatoses*;
Skin;
Ulcer
- From:Annals of Dermatology
1991;3(2):119-125
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report two cases of malignant schwannoma of skin in association with non-familial neurofibromatosis. Case 1, a 47 year old man, had a large subcutaneous tumor on the sacral area and case 2, a 62 year old woman, a painful, ulcerating tumor on the posterior aspect of the left arm. Both cases were histopathologically confirmed as malignant schwannomas and immunohistochemical studies showed 5-100 protein in the tumor cells. After surgical excision of the tumors, case 1 was lost to follow up, while case 2 remained without evidence of disease for more than one and half years.