MSCT perfusion study of whole-liver based on Couinaud’s hepatic segments in normal liver
10.3969/j.issn.1002-1671.2015.04.014
- VernacularTitle:基于正常肝脏 Couinaud 分段的MSCT 全肝灌注研究
- Author:
Mengdi LI
;
Yong CHEN
;
Kai ZHU
;
Zhiling GAO
;
Xin YIN
- Publication Type:Journal Article
- Keywords:
CT perfusion imaging;
liver;
hemodynamics
- From:
Journal of Practical Radiology
2015;(4):575-579
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the blood flow charateristics of normal Couinaud’s hepatic segments by using whole-liver perfu-sion with multi-slice spiral computed tomography (MSCT).Methods 73 patients underwent whole-liver perfusion enhanced CT scans for detection of gastric or pancreas cancer,and some were excluded including metastatic liver tumors in 7,multiple liver cysts (>3 cm in diameter)in 6,cirrhosis in 6,liver operation or splenecormy in 3,intra-hepatic bile duct dilation in 1,and excessive motion artifacts in 4.The final 46 patients with normal liver were included,and the perfusion parameters of liver segments were measured for estimating blood-dynamics condition.Results The hepatic arterial perfusion (HAP)in segment 3 was significantly higher than that in segment 6,7 and 8 (P <0.05),and the HAP in segment 4 was significantly higher than that in segment 7 (P <0.05).The hepatic perfusion index (HPI)in segment 3 was significantly higher than that in segment 7 (P <0.05).All normal liver were classi-fied into two groups (group A:<60 years,group B:≥60 years),and no significant correlation between age groups was found.How-ever,the perfusion parameter values in group A were higher than those in group B.No significant correlation was found between gen-ders.Conclusion Our results suggest that differences exist in normal hepatic parenchyma between liver segments.MSCT whole-liver perfusion imaging can more comprehensively response hemodynamic changes in liver,and provids the imaging basis for clinical evaluation of liver disease.
