A Case of Cytophagic Histiocytic Panniculitis.
10.5021/ad.1991.3.2.133
- Author:
Dong Won LEE
;
Byoung Chan PARK
;
Dong HOUH
;
Si Yong KIM
;
Hyung Ok KIM
;
Chung Won KIM
- Publication Type:Case Report
- Keywords:
Bean bag cell;
Cytophagic histiocytic panniculitis
- MeSH:
Bone Marrow;
Female;
Fever;
Hemorrhagic Disorders;
Histiocytes;
Humans;
Liver Diseases;
Muramidase;
Panniculitis*;
Young Adult
- From:Annals of Dermatology
1991;3(2):133-137
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cytophagic histiocytic panniculitis(CHP) is a histiocytic disorder that was first described by Winkelmann and Crotty in 1980. We have recently experienced a case of CHP is a 21-year-old female who had developed recurrent fever and erythematous tender subcutaneous nodules, progressing to liver dysfunction and hemorrhagic diathesis. Histopathologically, infiltrates of large cytophagic histiocytes lacking atypia were present in the subcutis. Hemophagocytic histiocytes were observed in the bone marrow. Immunohistochemical studies were performed, and revealed positive immunoreactivity for lysozyme and T cell marker in the subcutaneous inflammatory lesions.
