Clinical significance of urine micro albumin and urine enzyme detections in early renal injury in children with allergic purpura
10.3969/j.issn.1673-4130.2015.05.010
- VernacularTitle:尿微量蛋白和尿酶测定在过敏性紫癜患儿早期肾损伤中的临床意义
- Author:
Lishu DU
;
Longyu PING
;
Wei XIONG
- Publication Type:Journal Article
- Keywords:
allergic purpura;
kidney injury;
urinary enzymes
- From:
International Journal of Laboratory Medicine
2015;(5):599-600
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical significance of the urine micro albumin(MA)and urine enzyme detections in early renal injury in children with allergic purpura.Methods 120 patients with allergic purpura were chosen as the research sub-jects and divided into the early renal injury group and non-renal injury group according to whether having the renal injury.Contem-poraneous 40 healthy children were chosen as the healthy control group.The urine MA and urine enzyme levels were detected and compared among the various groups.Results MA was (17.5 ±3.8)mg/L in the study group,transferring(TRF)was (0.56 ± 0.34)mg/L,β2-MG was (0.35 ±0.07 )mg/L,NAG was (18.6 ±5.1 )U/g,which were significantly higher than those in the healthy control group,the differences were statistically significant (P <0.05 );in the early renal injury group,MA was (42.1 ± 21.3)mg/L,TRF was (1.65±0.54)mg/L,β2-MG was (0.43±0.06)mg/L and NAG was (23.1±5.12)U/L,which were signif-icantly higher than those in the non-renal injury group,the differences had statistically significance (P <0.05).Conclusion The de-tection of urine MA and urine enzyme can be used as the indexes for monitoring the early renal injury in children with allergic pur-pura,and is conducive to early discovery,in time intervention and reduce the occurrence of complications.
