Analysis on effects of drug resistance control countermeasures
10.3969/j.issn.1673-4130.2015.05.037
- VernacularTitle:耐药性控制对策的成效分析
- Author:
Lingli GU
- Publication Type:Journal Article
- Keywords:
control of drug resistance;
comprehensive measures;
efficacy evaluation
- From:
International Journal of Laboratory Medicine
2015;(5):662-664
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the effects of drug resistance control countermeasures and the existing problem to provide the scientific basis for containing the drug resistance.Methods Hospital adopted a series of the comprehensive countermeasures for controlling the drug resistance during 2012-2013.The drug resistance rate of top three bacterial strains isolated from the inpatient department and ICU during these two years,submitted examination rate of specimens,consumption amount of hand hygiene prod-ucts per hospitalization day,the prevalence rate,times of the early warning of the hospital infection;use rate of antibacterial drugs, use density of antibacterial drugs and detection rate of the important drug-resistant bacteria were analyzed and their changes during these two years were compared.Results The drug resistance rate of the top three bacteria isolated from the inpatient department of the whole hospital was decreased during these two years,the difference was statistically significant(P <0.05).The resistance rate in ICU except ABA had statistical difference (P <0.05).The examination rate of specimens and the amount of hand hygiene prod-uct consumption per hospitalization day were increased year by year;the prevalence rate and the times of the early warning of the hospital infection remained stable;the use rate of antibacterial drugs,use density of antibacterial drugs and detection rate of the im-portant drug-resistant bacteria showed the decreasing trend.Conclusion A series of comprehensive drug resistance control meas-ures have the effects in this hospital,but the little effect in ICU.The prevalence rate and the times of the early warning of the hospi-tal infection remain stable,the use rate of antibacterial drugs,use density of antibacterial drugs and detection rate of the drug-resist-ant bacteria are decreased.The countermeasures should be continuously improved for controlling the generation of drug resistance.
