Clinicopathologic prognostic factors in renal cell carcinoma.
- Author:
Jin Seon CHO
1
;
Sang Kon LEE
;
Jin Moo LEE
Author Information
1. Department of Urology, College of Medicine, Hallym University, Korea.
- Publication Type:Original Article
- Keywords:
Renal cell carcinoma;
Prognostic factor;
Survival
- MeSH:
Carcinoma, Renal Cell*;
Humans;
Lymph Node Excision;
Lymphatic System;
Neoplasm Metastasis;
Nephrectomy;
Renal Veins;
Rivers;
Survival Rate
- From:Korean Journal of Urology
1991;32(4):545-550
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
From 1980 to 1989, 144 patients underwent radical nephrectomy for renal cell carcinoma. Survival was analyzed in terms of pathologic stage and histologic grade. Data revealed that M category was the most important prognostic factor followed by, in order of importance, T category, N category, and grade. But grade as prognostic factor in renal cell carcinoma needs additional investigation. Stage pT1 and pT2 showed similar survival rate. The separation of pT1 and pT2 according to size of the primary tumor may not be a meaningful prognostic variable. Because vascular invasion may occur with tumors of various size, separating components into a description of the tumor (T), nodes (N), metastases (M) and renal vein involvements (V) makes good sense. The prognostic value of lymphadenectomy is limited by the fact that the tumor metastasizes through the blood stream and the lymphatic system with equal frequency.
