Somatic symptoms and dynamic changes after treatment in elderly inpatients with depression:A 1-year follow-up study
10.3969/j.issn.1000-6729.2015.03.009
- VernacularTitle:抑郁障碍住院老年患者的躯体症状及治疗后转归的1年随访
- Author:
Guichun ZHAO
;
Ying LIANG
;
Xiao WANG
;
Tao LI
;
Yao CHENG
;
Xinyu SUN
- Publication Type:Journal Article
- Keywords:
later-life depression;
somatic symptoms;
treatment outcome;
fllow-up stadies
- From:
Chinese Mental Health Journal
2015;(3):204-209
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the characteristics of somatic symptoms and their dynamic changes after treatment in elderly inpatients with depression,so as to give supported data in differential diagnosis and management of somatic symptoms in the elderly patients.Methods:Totally 69 consecutively hospitalized depression patients(≥60 years)were enrolled in the study,and 62 of them completed the 12-month follow-up.The diagnoses were made according to International Statistical Classification of Diseases and Related Health Problem-10th revision(ICD-10) criteria.The Hamilton Depression Scale(HAMD),Hamilton Anxiety Scale(HAMA)and Somatic Symptom Self-rat-ing Scale-Somatic factor(SSS-S)were used to assess the severity of depression,anxiety and somatic symptoms, which were evaluated at baseline,2 weeks,4 weeks and the end of 12-monthr espectively.The Minimum Mental State Examination(MMSE)were used to evaluate cognitive function,and Global Assessment Function(GAF)were used to evaluate social function at the end of 12-month follow-up.Result:Somatic symptoms presented in the all patients at the stages of depressive episode.The most common ones were gastrointestinal symptoms(91%),dizzi-ness or headache(66%),cardiovascular symptoms(59%).SSS-S scores at 2 weeks and 4 weeks of antidepressant treatment were significantly improved compared with those of baseline,[(13.6 ±3.2),(12.4 ±2.8)vs.(17.1 ± 4.8),analyzed by repeated measures of ANOVA,P <0.05].The changes of SSS-S scores were positive associated to the changes of anxiety symptoms and the effect of physical diseases,analyzed by hierarchical linear model analy-sis.At the stages of rehabilitation,residual somatic symptoms were positive associated to the degree of anxiety symptoms(OR =2.132,P <0.05),and unrelated to the level of HAMD,MMSE and GAF scores analyzed by logis-tic regression analysis.Conclusion:Somatic symptoms are various in elderly inpatients with depression during the a-cute phase,which are improved greatly as effective antidepressant treatment,and still have residual somatic symp-toms at the stage of rehabilitation.The effect of physical diseases and anxiety symptoms have influence on somatic symptoms.
