Side effects of pemetrexed in the maintenance therapy of nonsmall-cell lung cancer at advanced stage and the nursing measures
10.3969/j.issn.1671-8283.2015.05.016
- VernacularTitle:培美曲塞维持治疗晚期非小细胞肺癌的不良反应观察及护理
- Author:
Ruqiong WEI
;
Gaohua LI
;
Xiao LU
;
Guozhen LING
- Publication Type:Journal Article
- Keywords:
pemetrexed;
nonsmall-cell lung cancer;
nursing
- From:
Modern Clinical Nursing
2015;(5):48-50
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the side effects of pemetrexed in the maintenane therapy of nonsmall-cell lung cancer (NSCLC) at advanced stage and summarize the nursing measures. Methods Fifty-one NSCLC patients were treated maintenance therapy by pemetrexed. The side effects were observed and corresponding nursing measures were taken. Results The side effects included bone marrow depression of 33 cases, adverse reactions in gastrointestinal tract of 14 cases, and skin rashes of 4 cases, all at the degree of I-II. All of them were alleviated after active treatments. Conclusion Such nursing measures as close of side effects and careful nursing to the NSCLC patients treated with maintenance therapy with temetrexed are main measures for the success of treatment.