Spectrum construction of differently-expressed novel microRNA in SLE patients and function analysis of its target genes
10.7652/jdyxb201502016
- VernacularTitle:构建 SLE 患者 novel microRNA 差异性表达谱及其靶基因的功能分析
- Author:
Wenbiao CHEN
;
Yong DAI
;
Xin ZHONG
;
Suhui YE
;
Guifang HE
;
Hui MIU
;
Yanbo QIU
;
Zhaohui LI
- Publication Type:Journal Article
- Keywords:
systemic lupus erythematosus;
novel microRNA;
target gene;
different expression;
GO enrichment;
KEGG pathway
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2015;(2):225-231
- CountryChina
- Language:Chinese
-
Abstract:
binding,cellular organelle membrane,and cellular metabolic process of GO enrichment.For the KEGG pathways, the target genes mainly concentrated on the focal adhesion pathway.Conclusion There is a different expression of novel microRNA between SLE and NC groups.The target genes from differently-expressed novel microRNA may play an important role in the pathogenesis of SLE and clinical symptoms and may be the unique target for further research.
