Effects of allergic and nonallergic rhinitis on bronchial inflammation
- VernacularTitle:不同类型鼻炎对下气道炎症的影响
- Author:
Wei CHEN
;
Yong ZHANG
;
Zhiyi WANG
;
Kunmin WU
;
Junfeng JI
;
You CHENG
;
Qiuping WANG
;
Tianyou WANG
- Publication Type:Journal Article
- Keywords:
Allergic rhinitis;
Nonallergic rhinitis;
Bronchial inflammation;
Induced sputum
- From:
Journal of Medical Postgraduates
2015;(2):178-181
- CountryChina
- Language:Chinese
-
Abstract:
Objective To describe the effects of allergic and nonallergic rhinitis on patients with bronchial inflammation by comparing the bronchial inflammation characteristics . Methods All patients enrolled in the study were categorized into two groups according to rhinitis diagnostic criteria , 377 cases in the allergic rhinitis ( AR) group, 262 cases in non-allergic rhinitis ( NAR) group and another 264 patients without rhinitis as control group .Induced sputum differential cytology tests , exhaled nitric oxide concentration measurements and methacholine bronchial provocation tests were performed .The characteristics and differences in lower airway inflam-mation among the three groups were compared . Results The exhaled nitric oxide level and the positive rate of the exhaled nitric ox-ide were different significantly in AR group and NAR group than the control group (P<0.05);Bronchial provocation positive rate was 12.20%in AR group, and 6.10%in the NAR group, the difference was significant (P<0.05), and the levels in the two groups were significantly higher than the control group (P<0.05).AR group and NAR group has a significant different (P<0.05) propor-tions of eosinophil in induced sputum , while the positive rate of eosinophil in induced sputum was not different significantly ( P >0.05). Conclusion Bronchial inflammation may be aggravated by AR and NAR , so all patients with AR and NAR need treatment , and the degree of inflammation was higher in AR patients than the NAR patients .
