Efficacy of combined metformin and other hypoglycemic drugs
10.3969/j.issn.1006-6187.2015.02.019
- VernacularTitle:二甲双胍联合治疗临床疗效的研究进展
- Author:
Wolin HOU
;
Fang LIU
- Publication Type:Journal Article
- Keywords:
Metformin;
Combination therapy;
Hypoglycemic agent;
Efficacy
- From:
Chinese Journal of Diabetes
2015;(2):178-181
- CountryChina
- Language:Chinese
-
Abstract:
Metformin was widely recommended as a first‐line drug for patients with type 2 diabetes mellitus(T2DM ). However ,studies have shown that patients who start metformin as monotherapy often required additional agents to maintain glycaemic control with the natural progression of T 2DM. Anti‐diabetic agents may be used in combination with metformin ,including sulfonylureas ,glinides , thiazolidinediones(TZDs) ,α‐glucosidase inhibitor (AGDI) ,dipeptidyl peptidase‐4 inhibitor (DPP‐4) and glucagon‐like peptide‐1 (GLP‐1 ) or insulin. This paper mainly reviews the recent studies about the therapeutic effect of metformin in combination with other anti‐diabetic agents.
