Relationship between hypertriglyceridemic-waist phenotype and clustering of cardiovascular risk factors in adolescents
10.3760/cma.j.issn.1000-6699.2015.02.001
- VernacularTitle:青少年高甘油三酯血症-腰围表型与心血管危险因素聚集相关
- Author:
Chunming MA
;
Xiaoli LIU
;
Guoqin GAO
;
Rui WANG
;
Fuzai YIN
;
Yue LIU
;
Gailing HAN
;
Cuijuan WANG
;
Na LU
;
Qiang LU
- Publication Type:Journal Article
- Keywords:
Hypertriglyceridema;
Waist circumference;
Risk factors;
Adolescents
- From:
Chinese Journal of Endocrinology and Metabolism
2015;(2):95-98
- CountryChina
- Language:Chinese
-
Abstract:
Objective The aim of the study was to explore the relationship between hypertriglyceridemic-waist(HTWC) phenotype and clustering of cardiovascular risk factors in adolescents. Methods A cross-sectional study was conducted in 3 136 Han adolescents aged 13-17 years in Qinhuangdao. The HTWC phenotype was defined as serum triglyceride concentrations ≥1. 47 mmol/ L and waist circumference ≥90 th percentile for age and sex. Results The prevalence of HTWC phenotype was 3. 3% . The prevalence of clustering of cardiovascular risk factors was 0. 4%in adolescents with normal waist circumference and serum triglyceride and 14. 7% in adolescents with HTWC phenotype. After adjustment for sex, age, body mass index, and family history of diabetes and hypertension, the prevalence of clustering of cardiovascular risk factors in adolescents with HTWC phenotype was 9. 286 fold(95% CI 3. 161-27. 282, P<0. 01) of that in adolescents with normal waist circumference and triglyceride. Conclusion There was a significant correlation between HTWC phenotype and clustering of cardiovascular risk factors, suggesting that this phenotype may be applied as a simple marker for identifying adolescents with clustering of cardiovascular risk factors.