Influence of trimetazidine on prognosis of patients with X syndrome
10.3969/j.issn.1008-0074.2015.01.17
- VernacularTitle:曲美他嗪对X综合征患者预后的影响
- Author:
Jinshuang LI
;
Wanhong WANG
;
Yong CHENG
- Publication Type:Journal Article
- Keywords:
Microvascular Angina;
Trimetazidine;
Prognosis
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2015;24(1):59-61
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the influence of trimetazidine (TMZ)combined traditional routine drugs on progno-sis of patients with cardiac syndrome X.Methods:A total of 80 patients with cardiac syndrome X were randomly and equally divided into routine treatment group and TMZ group (received TMZ 20mg,three times/d based on routine medication).Both groups were treated for 12 weeks.Patients of two groups received treadmill exercise test and car-diac function examination before and after treatment,and the results were statistically compared.Results:Com-pared with routine treatment group after treatment,there were significant rise in total exercise time [(7.90±1.45) min vs.(9.35±1.70)min]and the time ST segment depressed 1mm [(5.30±1.43)min vs.(6.78±2.00)min], and significant reduction in ST segment depression extent [(0.89±0.30)mm vs.(0.61±0.20)mm],P <0.05 all;for cardiac function,there were significant rise in stroke volume [(67.99±11.77)ml vs.(74.05±7.58)ml]and left ventricular ejection fraction [(50.13±11.05)% vs.(56.02±9.52)%]in TMZ group,P <0.01 all.Conclusion:TMZ can significantly improve prognosis of patients with cardiac syndrome X.
