The efficacy of calcined natural bovine bone(CBB)in the treatment of bone defects in animal
10.3969/j.issn.1001-3733.2015.02.04
- VernacularTitle:天然煅烧骨修复材料(骼瑞)修复动物骨缺损的有效性研究
- Author:
Yue HE
;
Zhiquan TIAN
;
Liang WANG
;
Yang YAO
;
Lu YANG
;
Wentao HUANG
;
Xinhui HUANG
- Publication Type:Journal Article
- Keywords:
Calcined Bovine Bone;
Repair ofalveolar bone defects;
Repair ofcritical sized cranial defect
- From:
Journal of Practical Stomatology
2015;(2):167-170
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the efficacy of calcined bovine bone(CBB)in the repair of animal bone defects.Methods:Ca-nine alveolar bone defect model,rat and rabbit calvarial critical size defect models were established respectively.All animals were randomly divided into 2 groups(n=6).The defects in the experimental group were repaire with CBB,those in the control group were not treated.The effects were observed by HE staining,Micro CT and Masson trichrome staining.Results:Canin alveolar bone de-fects were well repaired 8 week after operation.The skull defects in rabbits and SD rats were replaced by new bone 1 2 and 8 weeks after operation respectively.In all the control groups bone defects were not healed or not completely repaired.Conclusion:CBB is ef-fective in the repair of bone defects.