Effect of serum immunoglobulin M and superoxide dismutase by percutaneous epidural steroid injections in patients with lumbar disc herniation
- VernacularTitle:经皮硬膜外类固醇注射对腰椎间盘突出患者血清免疫球蛋白和超氧化物歧化酶的影响
- Author:
Zhong ZHOU
;
Feng CHEN
;
Lin JIANG
- Publication Type:Journal Article
- Keywords:
steroid;
lumbar disc herniation;
immunoglobulin;
superoxide dismutase
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(3):128-130
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss effect of serum immunoglobulin M (IgM) and superoxide dismutase (SOD) by percutaneous epidural steroid injections in patients with lumbar disc herniation.Methods 137 patients with lumbar disc herniation were selected in Central of Hospital of Wuhan,all patients were randomly assigned joint group and O3 group, all patients were given ozone (O3) injection treatment, before treatment the joint group was given percutaneous epidural steroid injections, the joint group on the basis of O3 injection method was divided into multi-way group and routine group, followed up for 6 months, analyzed all patients therapeutic effect and recurrence rate,used enzyme-linked immunosorbent method to detect patients with serum IgM, SOD level, Pearson analysis method was used to analyze the relationship between the two groups.Results The joint group treatment effective rate was 91.89%, O3 group treatment effective rate was 79.73%, the former was higher than the latter, the difference was statistically significant ( P<0.05), The joint group serum IgM, SOD level was better than O3 group(P<0.05), In six months, multi-way group recurrence rate was 10.81%, routine group recurrence rate was 18.92%,O3 group recurrence rate was 31.08%, multi-way grou P