Safety and Short-term Efficacy of Laparoscopic Assisted Distal Gastrectomy versus Open Distal Gastrectomy in D2 Radical Surgeries for Locally Advanced Distal Gastric Cancer:A Meta-analysis
- VernacularTitle:腹腔镜辅助与开腹胃癌D2根治术治疗局部进展期远端胃癌的安全性及近期疗效Meta分析
- Author:
Hongyan WANG
;
Xiaodan ZHAO
;
Guosheng LI
;
Yuan FU
;
Lirun KUANG
;
Shijian CUI
;
Zhengrong LIU
- Publication Type:Journal Article
- Keywords:
radical surgery for gastric cancer;
laparoscopic operation;
Meta-analysis
- From:
Journal of China Medical University
2015;(3):252-258
- CountryChina
- Language:Chinese
-
Abstract:
Objective To conduct a Meta?analysis to compare the safety and short?term efficacy of laparoscopic assisted distal gastrectomy (LADG)and open distal gastrectomy(ODG)in D2 radical surgeries for locally advanced distal gastric cancer. Methods The literatures from Janurary,1990 to August,2014 on the evaluation of safety and short?term efficacy of LADG versus ODG in D2 radical surgeries for locally advanced distal gastric cancer were collected. The quality of the enrolled articles was evaluated and the software Revman 5.2 was adopted to analyze the cura?tive effect. Results Totally 25 articles met the inclusion criteria,including 5 044 patients with treatment of D2 radical surgeries for locally advanced distal gastric cancer. There was no significant difference in the cleaning number of lymph nodes between LADG and ODG in patients undergoing D2 radical surgeries for locally advanced distal gastric cancer. The operation time was longer for LADG than ODG,but the postoperative evaluation in?dexes such as the intraoperative blood loss and the short?term efficacy of LADG were superior to ODG. Conclusion In the treatment of locally ad?vanced distal gastric cancer,there were differences in the safety and short?term efficacy between LADG and ODG,and surgeons should give concern to these differences in clinical practice to select appropriate surgical approaches. Further research is still needed to explore the long?term efficacy.
