Research progress of strategies for transplantation-eligible multiple myeloma patients

VernacularTitle:适合移植的多发性骨髓瘤患者治疗研究进展
Author: Huan GUO
Publication Type:Journal Article
Keywords: Multiple myeloma; Therapy protocols; Hematopoietic stem cell transplantation
From: Journal of Leukemia & Lymphoma 2014;23(9):564-566
CountryChina
Language:Chinese
Abstract: For transplantation-eligible multiple myeloma patients,induction treatment of triple drug regimens followed by the collection of hematopoietic stem cells is generally recommended.For transplantationeligible patients,high-dose melphalan remains the standard regimen.Consolidation after transplantation has shown an improvement in response rates.Maintenance therapy with bortezomib or lenalidomide (or both in very-high-risk patients) is a reasonable option for long-term disease control and improvement in overall survival.Application of new agents into therapy of multiple myeloma should result in improved outcomes and long-term disease control.