Blood products and its applications for the treatment of military trauma and diseases
10.7644/j.issn.1674-9960.2015.03.001
- VernacularTitle:血液制品及其在伤病救治中的应用
- Author:
Jingang ZHANG
- Publication Type:Journal Article
- Keywords:
blood products;
plasmaderiviatives;
albumin;
universal virus inactivated freeze-dried plasma;
specific immu-noglobulin;
coagulation factors
- From:
Military Medical Sciences
2015;(3):161-164
- CountryChina
- Language:Chinese
-
Abstract:
The first blood product albumin was developed during World War Ⅱ.Since then, blood products began to play an irreplaceable role in military trauma and emergency cares .Currently, the supporting system of blood and blood products has become increasingly sophisticated .Development of novel blood products also improved dramatically .Universal virus inactivated freeze-dried plasma has also been purchased by the military .Albumin is used as antishock blood volume expansion for emergency treatment of military trauma .Different kinds of albumin including albumin of various concentra-tions, high purity albumin and albumin in soft packages are available .Specific immunoglobulin has become the regular stra-tegic storage of some developed countries , used for the prevention and treatment of infection in military trauma , emerging infectious diseases and against the potential threat of bioagents and bioterrorism .Local hemostatic produced upon fibrinogen and thrombin as well as coagulator Factor Ⅶperforming integral hemostasis effect have become increasingly significant for treating hemorrhage in military trauma .Development of anticoagulants including human protein C and antithrombin has got great improvement .These medicines have the potential for preventing and treating sepsis caused by military trauma .Prote-ase inhibitors including α2-macroglobulin are expected to work in the specific medicine .In conclusion , blood products will play a greater role in the future war and non war military operations .
