Nursing of patients with acute hepatic graft versus host disease after allogeneic hematopoietic stem cell transplantation

VernacularTitle:异基因造血干细胞移植后急性移植物抗宿主病患者的护理
Author: Jin ZHOU ; Bin WU ; Youshan ZHANG
Publication Type:Journal Article
Keywords: allogeneic-hematopoietic stem cell transplantation; graft versus host disease; nursing
From: Modern Clinical Nursing 2015;(2):21-24
CountryChina
Language:Chinese
Abstract: Objective To explore the measures for nursing patients with acute hepatic graft versus host disease (aGVHD) after allogeneic hematopoietic stem cell transplantation. Method The clinical data of 54 patients with aGVHD after hematopoietic stem cell transplantation during January 2010 and December 2013 were reviewed for summing up the nursing measures. Results In the study, 160 patients underwent allogeneic-hematopoietic stem cell transplantation and 53 of them contracted with acute hepatic-versus-host disease. Among them, 2 cases were at degreeⅣ, 10 at degreeⅢ, 23 at degreeⅡand 19 at degreeⅠ. Forty-seven cases(87.01%) were cured after careful treatment and care , 3 ( 5 . 56%) developed into cGVHD and 4 ( 7 . 41%) died . Conclusion Enhanced observation and postoperative nursing of liver, intestine and skin together with performance of mental care and dietary nursing are effective in achieving satisfactory outcomes of GVHD.