Clinical significance of serum Cys-C,β2-MG and RBP detection in hemorrhagic fever with renal syndrome
10.3969/j.issn.1673-4130.2015.06.029
- VernacularTitle:肾综合征出血热患者血清Cys-C、β2-MG、RBP检测的临床意义
- Author:
Jinge LI
;
Ziyue LI
;
Huizhong ZHANG
;
Jianjun SHEN
- Publication Type:Journal Article
- Keywords:
cystatin C;
β2 microglobulin;
retinol binding protein;
hemorrhagic fever with renal syndrome
- From:
International Journal of Laboratory Medicine
2015;(6):784-785
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes condition and clinical significance of serum cystatin C(Cys‐C) ,β2 microglobulin(β2‐MG) and retinol binding protein (RBP) detection in different stages of hemorrhagic fever with renal syndrome(HFRS) .Methods The levels of serum Cys‐C ,β2‐MG and RBP were detected in 22 patients with HFRS and 30 cases of healthy physical examination and the detection results were statistically analyzed by the SPSS13 .0 software .Results The serum Cys C and β2‐MG levels in every stage of HFRS were increased compared with the healthy control group(P< 0 .05) ,which in the oliguria stage was most significant (P< 0 .01) .RBP had no significant differences in the fever stage and shock stage compare with the healthy control group (P >0 .05) ,while RBP was significantly increased in the oliguria stage ,polyuria stage and convalescence stage(P< 0 .01) ,but no statisti‐cally significant differences among the three stage(P> 0 .05) .Conclusion β2‐MG is more sensitive than Cys‐C in the early stage of HFRS ;RBP has the clinical guidance significance in the progression of HFRS .
