Research progress of inducible nitric oxide synthase/cyclooxygenase-2 in female stress urinary incontinence
- VernacularTitle:诱导型一氧化氮合酶／环氧合酶2在女性压力性尿失禁中的研究进展
- Author:
Zhiming YANG
;
Kewei FANG
- Publication Type:Journal Article
- Keywords:
Inducible nitric oxide synthase;
Cyclooxygenase 2;
Stress urinary incontinence;
Nitric Oxide;
Prostaglandins;
Lower urinary tract
- From:
Journal of Medical Postgraduates
2015;(3):323-328
- CountryChina
- Language:Chinese
-
Abstract:
Inducible nitric oxide synthase (iNOS), cyclooxygenase 2 (COX-2) and iNOS/COX-2 signal transduction path-ways are closely related to occurrence and development of diseases , such as tumor, immunity, inflammation, hypoxia, ischemia, injury and so on.iNOS/COX-2 controls the physiological and pathological activities of human lower urinary tract .This article summarizes the role and mechanism of iNOS/COX-2 signal transduction pathways in related diseases .It not only provids an important target for treat-ment of disease and but provides a theoretical basis and research ideas for the development and research of new drugs .
