Chorea in Systemic Lupus Erythematosus: Evidence for Bilateral Putaminal Hypermetabolism on F-18 FDG PET.
- Author:
Wook Jang SEO
1
;
Son Mi CHUNG
;
Su Jin KOH
;
Chang Keun LEE
;
Jae Seung KIM
;
Joo Hyuk IM
;
Bin YOO
;
Hee Moon BOM
Author Information
1. Department of Internal Medicine, Universitiy of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. byoo@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus;
Chorea;
F-18 FDG;
PET
- MeSH:
Antibodies, Antiphospholipid;
Aspirin;
Chorea*;
Female;
Follow-Up Studies;
Glucose;
Humans;
Lupus Erythematosus, Systemic*;
Metabolism;
Middle Aged;
Putamen;
Tomography, Emission-Computed, Single-Photon
- From:Korean Journal of Nuclear Medicine
2003;37(5):325-330
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We describe a 54-year-old woman with systemic lupus erythematosus (SLE) who suddenly presented with chorea and had positive antiphospholipid antibodies. F-18 FDG PET showed abnormally increased glucose metabolism in bilateral putamen and primary motor cotex. Tc-99m ECD SPECT also showed abnormally increased regional cerebral blood flow in bilateral putamen. She was treated with corticosteroid and aspirin after which the symptoms improved. Four months later, follow up F-18 FDG PET showed improvement with resolution of hypermetabolism in bilateral putamen. This case suggests that striatal hypermetabolism is associated with chorea in SLE.
