Clinical and imaging characteristics of acute marchiafava-bignami disease
10.3969/j.issn.1671-8348.2015.08.016
- VernacularTitle:急性型胼胝体变性的临床表现和影像学特点
- Author:
De YANG
;
Yu LI
;
Xiaosu YANG
;
Liang HE
;
Keyu CHEN
- Publication Type:Journal Article
- Keywords:
marchiafava-bignami disease;
magnetic resonance imaging;
computed tomography
- From:
Chongqing Medicine
2015;(8):1060-1062
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the presentation and radiologic findings of acute marchiafava‐bignami disease(MBD) . Methods Three cases of acute MBD who were diagnosed and treated in our hospital were retrospectively analyzed ,including the clinical symptoms ,laboratory tests ,imaging examination(such as cranial CT ,magnetic resonance imaging(MRI) ,prognosis .Results Three cases were acute onset .The symptoms may be non‐specific ,such as consciousness disorder ,psychosis ,seizures ,delirium tremor and high fever .The imaging changes in the genu and splenium of corpus callosum could be found ,even in the bihemispheric white matter of all cases .CT revealed low‐density areas ,meanwhile MRI showed iso‐or hypo‐intensity on T1WI and ADC ,hyper‐in‐tensity on T2WI and fluid attenuated inversion recovery and restricted diffusion weighted imaging .The lesions involved in bihemi‐spheric brachium pontis in one case and in the body of corpus callosum in another case .Conclusion Acute MBD may present with various clinical forms ,but have characteristic imaging findings .
