Sero-epidemiological investigation of Enterovirus 71 antibodies in Fujian Province,China,2010
10.3969/cjz.j.issn.1002-2694.2015.03.008
- VernacularTitle:2010年福建省肠道病毒71型血清流行病学调查
- Author:
Jinzhang WANG
;
Wei CHEN
;
Yuwei WENG
;
Wenxiang HE
;
Yongjun ZHANG
;
Meng HUANG
;
Jianfeng XIE
;
Kuicheng ZHENG
;
Yansheng YAN
- Publication Type:Journal Article
- Keywords:
Enterovirus 71;
neutralizing antibody;
seroepidemiology survey
- From:
Chinese Journal of Zoonoses
2015;(3):227-231
- CountryChina
- Language:Chinese
-
Abstract:
In order to investigate EV71 antibody levels among general population from Fujian Province after the 2008‐2009 HFMD epidemics ,390 sera‐specimens were collected from 390 participants in 2010 .EV71‐specific antibody was detected by neutralization test ,indicating 186 (47 .69% ) sera of 390 were EV71‐seropositive .Although the difference by gender was not statistically significant on positive rates and antibody titers ,significant differences were observed in positive rates and antibody titers among age groups .The positive rate was increasing with age ,while the 0 age‐group yielded the lowest positive rate of 16 .67% .Subsequently ,significant difference was detected among positive rates and antibody titers between age groups of 0 to 4 years‐old and 5‐years‐old ,with the positive rate of 25 .33% and 61 .67% ,respectively .Therefore ,the EV71 antibody levels among general population from Fujian Province after the 2008‐2009 HFMD epidemics was still in the low level ,especially the age groups of 0 to 4 years‐old .The epidemic of HFMD mainly caused by EV71 will still occur in the future ,and children under 5 years old are major susceptible population ,continuously intensive surveillance ,prevention and control are required .
