Clinical comparative analysis of juvenile dermatomyositis and adult dermatomyositis

VernacularTitle:儿童与成人皮肌炎临床对照分析
Author: Hong YU ; Chunxiao LI ; Chengyi JIANG ; Ruhong CHENG ; Peizhen HUANG ; Zhen ZHANG ; Dongbao ZHAO
Publication Type:Journal Article
Keywords: dermatomyositis; clinical feature; child
From: Journal of Clinical Pediatrics 2015;(3):234-237
CountryChina
Language:Chinese
Abstract: ObjectiveTo understand the difference in characteristics between juvenile dermatomyositis (JDM) and adult dermatomyositis (ADM).Methods Sixty-one cases of JDM were retrospectively analyzed and compared with 30 cases of ADM. Results The rashes were presented as the initial symptom in all expect one JDM patients. Gottron’s papules were presented in 90% JDM patients and 67% ADM patients. Calcium deposition was presented in 7% JDM patients and none of the ADM patients. The cardiovascular system was involved in 7 % JDM patients and 23% ADM patients. Cancer occurred in none of JDM patients and 13% ADM patients. In JDM and ADM patients, the ratio of elevated muscle enzymes from highest to lowest was LDH, hy-droxybutyric acid enzyme, CK-MB, AST, and CK. The positive ratio of magnetic resonance (MRI) all exceeded 80% in JDM and ADM groups. Two cases died in each group.Conclusions The clinical presentation of JDM is basically the same as that of ADM. The most common initial symptoms in JDM are skin rashes and Gottron's papules. Cardiovascular disease and cancer are less in JDM than in ADM. MRI is valuable in the diagnosis of DM.