Relationship between autoimmune thyroid disorders and thyroid cancer in children

VernacularTitle:儿童甲状腺癌与自身免疫性甲状腺疾病相关性研究
Author: Ling ZHANG ; Shuhong LI ; Jing ZHANG ; Guochun XU
Publication Type:Journal Article
Keywords: autoimmune thyroid disorders; thyroid cancer; child
From: Journal of Clinical Pediatrics 2015;(3):238-241
CountryChina
Language:Chinese
Abstract: ObjectiveTo investigate the relationship between autoimmune thyroid disorders (AITD) and thyroid cancer (TC) in children.Methods Clinical date from 68 patients who underwent thyroidectomy and were histologically conifrmed with TC were retrospectively analyzed from 2000 to 2008. Age, gender, nodular size, lymph node metastasis, and invasive status of thyroid cancer were compared between patients with and without AITD.Results In 68 patients with TC, 45.6% (31/68) patients had concurrent AITD. Compared with those without AITD, a greater female preponderance, older age, smaller tumour size, higher TSH values, higher TG values, shorter survival time, lower disease free survival rate, and higher relapse rate were found in patients with AITD (P<0.05).Conclusions AITD are associated with TC in children. Follow-up is suggested in children with AITD.