Neuropathological findings in 38 children with temporal lobe intractable epilepsy

VernacularTitle:38例儿童颞叶难治性癫痫病理分析
Author: Jiangya WANG ; Wenling LI ; Jiang WU ; Huanfen ZHAO ; Jinli MAO ; Yan LOU
Publication Type:Journal Article
Keywords: temporal lobe; intractable epilepsy; focal cortical dysplasia; child
From: Journal of Clinical Pediatrics 2015;(3):265-268
CountryChina
Language:Chinese
Abstract: ObjectivesTo explore the neuropathological characteristics of children with temporal intractable epilepsy. MethodsA retrospective analysis of the pathological characteristics was conducted in 38 children who underwent epilepsy surgery from December 2011 to December 2013.ResultsAmong 38 patients, aged 2.5-14 years, 21 boys and 17 girls, 21 cases had focal cortical dysplasia (FCD), 1 case had FCDⅠa, 2 cases had FCDⅠb, 1 case had FCDⅡa, 3 cases had FCDⅡb, 5 cases had CDⅢa, 1 case had FCDⅢb, 1 case had FCDⅢc, 6 cases had FCDⅢd. Three cases had microdysgenesis, 3 cases had simple hippocampal sclerosis, 7 cases had neoplasms, 5 cases had dysembryoplastic neuroepithelial tumor, 2 cases had astroglioma, 2 cases had encephalitis, 2 cases had arachnoid cyst. ConclusionsFCD is the most common form that causes temporal lobe intractable ep-ilepsy in children. FCDIIId is the most common subtype in FCD.